Best CBD Oils: CBD For Arthritis And Joint Pain
A new scientific study got clever with its title that begins “Joints for joints.” Science writers are often funny, too! But this is often a crucial article, especially with all the questions people have about using CBD for arthritis and joint pain.
The importance of the article is two-fold. First, it’s a large-scale review of the present research on the utilization of cannabinoids for atrophic arthritis. Secondly, it had been published within the journal Current Opinion in Rheumatology. within the world of drugs, that’s an enormous deal—cannabinoids are going mainstream.
The pain of arthritis is due in large part to the inflammatory response. The pain, swelling, tenderness, and redness during a joint are classic signs of inflammation—and anything we will do to scale back the inflammation will reduce the pain and stiffness and help improve motion around the joint.
The key points within the article include:
.CBD acts as an anti-inflammatory substance by:
.Dampening the response by the system, which directly reduces inflammation
.Decreasing the number of inflammatory substances around the joint
“CBD is useful in decreasing inflammation and pain and might enhance the efficacy of therapeutic drugs.”
Does CBD oil work for all sorts of arthritis? Does CBD work for all sorts of joint pain? Well, the fast answer is yes—because all sorts of arthritis and joint pain are thanks to inflammation in some parts of the joint.
Types of Arthritis
The two commonest sorts of arthritis are osteoarthritis and atrophic arthritis. Osteoarthritis (OA) may be a sort of degenerative disease—that means age or overuse of joint leads to damage over time. atrophic arthritis (RA) is an autoimmune disease—where the system gets a misplaced signal and begins to attack your own body. In OA, cartilage begins to interrupt down due to injury, overuse, or aging; in RA, the system attacks the skinny tissue that lines the joints.
There are over 100 differing types of arthritis—some of the more common forms are Carpel Tunnel Syndrome, degenerative disc disease (which may be a common explanation for low back pain), fibromyalgia, gout, lupus, and arthritis-related to psoriasis.
All these sorts of arthritis have a minimum of one thing in common—inflammation. The inflammation irritates nerves and causes pain. Inflammation is such a central part of any sort of arthritis that the Arthritis Foundation recommends an anti-inflammatory diet that has been proven to assist reduce pain and inflammation.
Since CBD has anti-inflammatory properties, it seems reasonable that CBD is often useful for arthritis pain.
A Bit of History of Cannabis and therefore the Endocannabinoid System
Cannabis has been used as a medicinal plant for thousands of years, but THC (and then, later, CBD) were only “discovered” within the 1960s. within the late ‘80s, the endocannabinoid system, which is found in humans and animals, was described. It clothed that cannabis produces natural substances (think of them as keys) that would “fit” into receptors found on the surface of cells (think of the receptors as locks).
But what was this endocannabinoid system good for? What did it do?
It seems that the endocannabinoid system is active in quite a few roles: it’s a neighborhood to play in mood (you probably guessed that one), memory, the brain’s “reward” system the feel-good-about-yourself how cells answer insulin, the body’s response to worry, energy production, and inflammation—and pain. generally, the most endocannabinoids, Anandamide (AEA) and 2-Arachidonoylglycerol (2-AG) can bind to receptors on the surface of cells—there are two known receptors, CB1 and CB2.
AEA and 2-AG are made “on-demand” and act within the same area they were made. On top of that, they’re pretty quickly degraded, meaning that these endocannabinoids only act for a brief time.
Evidence that CBD Can Reduce Arthritis Pain
CBD for Osteoarthritis
Osteoarthritis is that the commonest sort of arthritis. it’s associated with aging, injury, and being overweight. the foremost common symptom is pain within the joint—this is worse after using the joint, worse later within the day, and after long periods of not using the joint. OA can occur in any joint, with the foremost common being the knee, spine (causing low back pain or neck pain), fingers, hips, and toes.
Animal studies clearly show that CBD can reduce the pain, inflammation, and damage related to osteoarthritis. There have only been a couple of human studies completed, but these have produced promising results:
an artificial sort of CBD was applied as a topical gel to treat knee pain in osteoarthritis. The results showed that pain decrease was important using the synthetic CBD gel.
A recent study using a web survey of chronic pain patients indicated that the utilization of CBD for osteoarthritis could reduce the utilization of opioids.
CBD for atrophic arthritis
Rheumatoid arthritis is an autoimmune disorder. Essentially, the system gets confused about what’s a traditional part of the body and what isn’t. due to this confusion, the system begins to wreck various targets—in the case of atrophic arthritis, the target is that the thin tissue lining the joints. Damage to the joints is thanks to both the direct damage from the immune cells and inflammation.
RA usually starts within the small joints of the hands and feet—leaving them tender, warm, red, and swollen. The pain is typically worse within the morning and after a period of rest. RA can then move to wrists, knees, ankles, elbows, hips, and shoulders, usually affecting each side of the body. RA also can damage the skin, eyes, lungs, heart, and other organs.
As it seems, CBD isn’t only an anti-inflammatory substance that reduces pain, but it also can act as an immunosuppressive agent and reduce the immune reaction.
Just as with osteoarthritis, the human studies on RA are just beginning.
.A preliminary study on Sativex, which contains CBD and THC during a 1:1 ratio (in an oral spray form), concluded that “a significant analgesic effect was observed and disease activity was significantly suppressed following Sativex treatment.”
.A recent review acknowledged that the cannabinoids, including CBD, have significant potential in treating diseases with both an immune and an inflammatory component, and therefore the review specifically mentioned RA as potentially taking advantage of CDB.
The conclusions were that using CBD for arthritis and joint pain may be a promising approach to pain relief.
How CBD Works on Arthritis Pain and Inflammation
We are still learning, and there are many details and many possibilities. Pain may be a complicated problem—there is a minimum of three different mechanisms for pain and a minimum of four major theories describing how pain is felt.
CBD appears to scale back pain in both direct and indirect ways—a good thing, because that likely means CBD can reduce different types of pain in arthritis and other diseases where joint pain is a problem.
.CBD can delay the degradation and reuptake of the naturally produced endocannabinoids AEA and 2-AG.
Antidepressants like SSRIs (selective serotonin reuptake inhibitors) work by increasing the amount of serotonin by decreasing the amounts sucked back to a neuron. CBD appears to figure within the same way. the top result’s that the endocannabinoids stay within the system longer—so the conclusion is that using CBD for arthritis should be effective.
.And CBD can support decrease the anxiety related to pain by activating serotonin sometimes referred to as the “happy hormone pathways. Anxiety is normally a part of the pain.
.CBD can interact with several different surface receptors (about 70 are identified so far). Overall, these interactions reduce inflammation and pain.
.CBD can affect the function of some receptors related to pain by changing the form of the receptor just a touch —it’s a bit like jamming a lock. When it does that, the important key won’t work also. during this case, meaning the feeling of pain isn’t transmitted to the brain also.
In summary, there seems to be an excellent deal of promise in using CBD for arthritis and joint pain, thanks to the way it decreases the inflammation related to the joints.
Review of Effects on CBD for Arthritis and Joint Pain
Animal studies are convincing, and that we are starting to see the results of the primary well-controlled and well-done human studies. Animal studies also are great to work out the possible side effects of CBD on animal models of arthritis. At the doses used, there appear to be only a few adverse effects—and those that were seen were very mild (nausea and fatigue for the foremost part and these tend to decrease with time). we’ve known for an extended time from many people’s experience with cannabis, that cannabinoids are often useful for reducing the pain and inflammation of arthritis. It’s nice to understand that the scientific world is catching up now!
Overall, using CBD for arthritis and other joint pain may be a promising approach and perhaps worth a try.